During the Middle Ages, the leading use of leg compression bandages was mainly for therapy. This is evidenced by the works of Avicenna (980–1037); Giovanni Michele Savonarola (1384–1468); Ambroise ParĂ© (1510–1590); Girolamo Fabrizio di Acquapendente (1537–1619); and other scientists. Guy de Chauliac in his book Chirurgica Magna described the use of compression bandages to treat enlarged veins of the legs.